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Studies

A Study showing antagonistic effect of Lactobacilli casei and Lactobacilli sporogenesis against some common pathogens- in vitro

P. Shukla, J. Sharma

Immunomodulatory activity of Lactobacillus sporogenes

V. Barbar, R. Thomas, M. Bhaskar

Effect of spore-bearing lactic acid-forming bacteria (Bacillus coagulans SANK 70258) administration on the intestinal environment, defecation frequency, fecal characteristics and dermal characteristics in humans and rats

K. Ara, S. Meguro, T. Hase, I. Tokimitsu, K. Otsuji, S. Kawai, S. Ito & H. Iino To

Safety evaluation of Bacillus coagulans SNZ 1969 in wistar rats

A. S. Metlakunta, R. J. Soman

Effect of freeze dried powdered probiotics on gingival status and plaque inhibition: a randomized, double-blind, parallel study

A. Yousuf, M. Sidiq, S. Ganta, A. Nagaraj, P. Vishnani, and I. Jan

In vitro evaluation of bioremediation capacity of a commercial probiotic, Bacillus coagulans, for chromium and lead toxicity

P. Belapurkar, P. Goyal, A. Kar

A comparative evaluation of the efficacy of Probiotic and chlorhexidine mouthrinses on clinical inflammatory parameters of gingivitis: a randomized controlled clinical study

P. V. Nadkerny, P. L. Ravishankar, V. Pramod, L. A. Agarwal, S. Bhandari

A Comparative Evaluation of Probiotics on salivary mutans Streptococci counts in indian children

G. Jindal, R.K. Pandey, J. Agarwal, M. Singh

Effect of Lactobacillus on the incidence and severity of acute rotavirus diarrhoea in infants. A prospective placebo-controlled double-blind study

R. Chandra

Preliminary observations on effect of Lactobacillus Sporogenes on serum lipid levels in hypercholesterolemic patients

J.C. Mohan, R. Arora, M. Khalilullah

Potential Probiotic Kluyveromyces marxianus B0399 Modulates the Immune response in caco-2 cells and peripheral blood mononuclear cells and Impacts the human gut microbiota in an In Vitro colonic model system

S. Maccaferri,a A. Klinder,b P. Brigidi,a P. Cavina,c and A. Costabileb

Halitosis Treatment Through the Administration of Antibiotic-Resistant Probiotic Lactic Yeast Kluyveromyces marxianus fragilis B0399 (K-B0399)

Cecchini, Nobili, Zanvit, Miclavez and Nobili

Effects of a fermented milk containing kluyveromyces marxianus B0399 and bifidobacterium lactis BB12 in patients with irritable bowel syndorme

A.Lisotti, G.L. Cornia, A.M. Morselli-Labate, A.Sartini, L.Turco, V.Grasso, P.Cavina, G.Mazzella, E.Roda

Draft Genome Sequence of the Probiotic Yeast Kluyveromyces marxianus fragilis B0399

S. Quarella,a P. Lovrovich,b S. Scalabrin,c I. Campedelli,a A. Backovic,b V. Gatto,a F. Cattonaro,c
A. Turello,b S. Torriani,a G. E. Felisa

IBS-associated Phylogenetic Unbalances of the Intestinal Microbiota Are Not Reverted by Probiotic Supplementation 

S. Maccaferri, M. Candela, S. Turroni, M. Centanni, M. Severgnini, C. Consolandi, P. Cavina, P. Brigidi

Antimicrobial activity of SYNBIO ® probiotic formulation in pathogens isolated from chronic ulcerative lesions: in vitro studies

M.M. Coman, L. Mazzotti, S. Silvi, A. Scalise, C. Orpianesi, A. Cresci, M.C. Verdenelli

Knowledge and acceptance of functional foods: A preliminary study on influence of a synbiotic fermented milk on athlete health

Coman M, Verdenelli C, Silvi S, Cecchini C, Gabbianelli R, Amadio E, Orpianesi C, Cresci A

Polyphenol content and in vitro evaluation of antioxidant, antimicrobial and prebiotic properties of red fruit extracts

M. M. Coman, A. M. Oancea, M. C. Verdenelli, C. Cecchini, G. E. Bahrim, C. Orpianesi, A. Cresci & S. Silvi

Impact of Probiotic SYNBIO® administered by vaginal suppositories in promoting vaginal health of apparently healthy women

M. C. Verdenelli, C. Cecchini, M. M. Coman, S. Silvi, C. Orpianesi, G. Coata, A. Cresci, G. C. Di Renzo

Effects of synbiotics on house dust mite allergic symptoms: A baseline-controlled open-label study

C. Cecchini, M.C. Verdenelli, S. Silvi, M.M. Coman, C. Orpianesi and G. Pascucci

Optimisation of the Measurement of the antioxidant activity of Probiotics and pathogens: a crucial step towards evidence-based assessment of health claims and production of effective functional foods

Cecchi T, Savini M, Silvi S, Verdenelli C & Cresci A

In vitro evaluation on HeLa cells of protective mechanisms of probiotic lactobacilli against Candida clinical isolates

M.M. Coman1,2, M.C. Verdenelli, C. Cecchini, S. Silvia, C. Orpianesi, M. Caspani, F. Mondello5 and A. Cresci

Evaluation of antipathogenic activity and adherence properties of human Lactobacillus strains for vaginal formulations

M.C. Verdenelli, M.M. Coman, C. Cecchini, S. Silvia, C. Orpianesi and A. Cresci

Probiotic-enriched foods and dietary supplement containing SYNBIO® positively affects bowel habits in healthy adults: an assessment using standard statistical analysis and support vector machines

S. Silvi, M. C. Verdenelli, C. Cecchini, M M. Coman, M S. Bernabei, J. Rosati, R. De Leone, C. Orpianesi, A. Cresci

Protective effects of probiotic Lactobacillus rhamnosus IMC501 in mice treated with PhIP

L. Dominici, M. Villarini, F. Trotta, E. Federici, G. Cenci, and M. Moretti

In vitro evaluation of antimicrobial activity of Lactobacillus rhamnosus IMC 501, Lactobacillus paracasei IMC 502 and SYNBIO® against pathogens

M.M. Coman, M.C. Verdenelli, C. Cecchini, S. Silvi, C. Orpianesi, N. Boyko and A. Cresci

Effect of buckwheat flour and oat bran on growth and cell viability of the probiotic strains Lactobacillus rhamnosus IMC 501®, Lactobacillus paracasei IMC 502® and their Combination SYNBIO®, in Synbiotic Fermented Milk

M. M. Coman, M. C. Verdenelli, C. Cecchini, S. Silvi, A. Vasile, G. E. Bahrim, C. Orpianesi, A. Cresci

Functional foods as carriers for SYNBIO ®, a probiotic bacteria combination

M. M. Coman, C. Cecchini, M. C. Verdenelli, S. Silvi, C. Orpianesi, A. Cresci

Influence of a combination of two potential probiotic strains, Lactobacillus rhamnosus IMC 501 and Lactobacillus paracasei IMC 502 on bowel habits of healthy adults

M.C. Verdenelli, S. Silvia, C. Cecchini, C. Orpianesi and A. Cresci

Effect of a probiotic intake on oxidant and antioxidant parameters in plasma of athletes during intense exercise training

D. Martarelli, M. C. Verdenelli, S. Scuri, M. Cocchioni, S. Silvi, C. Cecchini, P. Pompei

Inevstigation of the antigenotix properties of the probiotic Lactobacillus rhamnosus IMC 501® by gas chromato graphy-mass spectrometry

M.C. Verdenelli, M. Ricciutelli, F. Gigli, G. Cenci, F. Trotta, G. Caldini, A. Cresci and C. Orpianesi

Probiotic Properties of Lactobacillus rhamnosus and Lactobacillus paracasei isolated from human faeces

M. C. Verdenelli, F. Ghelfi, S. Silvi, C. Orpianesi, C. Cecchini, A. Cresci

Differences in Fecal Microbiota in different european study populations in relation to age, gender, and country: a cross-sectional study

S. Mueller, K. Saunier, C. Hanisch, E. Norin, L. Alm, T. Midtvedt, A. Cresci, S. Silvi, C. Orpianesi, M. C. Verdenelli, T. Clavel, C. Koebnick, H.-J. F. Zunft, J. Dore´,and M. Blaut

Soothing efficacy and tolerability of a skin care product containing live Lactobacillus rhamnosus bacteria and berry seed oils on atopic dermatitis lesions

B. Imko-Walczuk, A. Taraszkiewicz, A. Mäyrä

Probiotic compared with standard milk for high-caries children: A cluster randomized trial

G. Rodríguez, B. Ruiz1, S. Faleiros, A. Vistoso, M.L. Marró, J. Sánchez, I. Urzúa, and R. Cabello

Use of coconut water (Cocus nucifera L) for the development of a symbiotic functional drink

O. Segura-Badilla b, M. Lazcano-Hern

Severity of candida-associated denture stomatitis Is Improved in institutionalized elders who consume Lactobacillus rhamnosus SP1

X Lee, C Vergara, C P Lozano

Microbiological and clinical effects of probiotics and antibiotics on nonsurgical treatment of chronic periodontitis: a randomized placebocontrolled trial with 9-month follow-up

A. Morales, A. Gandolfo, J. Bravo, P. Carvajal, N. Silva, C. Godo, J. Garcia-Sesnich, A. Hoare, P. Diaz, J. Gamonal

Clinical Effects of Lactobacillus rhamnosus in non-surgical treatment of chronic periodontitis: a randomized placebo-controlled trial with 1-Year follow-up

A. Morales, P. Carvajal, N. Silva, M. Hernandez, C. Godoy , G. Rodriguez, R. Cabello, J. Garcia-Sesnich, A. Hoare, P. I Diaz, J. Gamonal

Supplementation with Lactobacillus rhamnosus SP1 Normalises Skin expression of genes implicated in insulin signalling and improves adult acne

G Fabbrocini, M Bertona, Ó Picazo, H Pareja-Galeano, G Monfrecola, E Emanuele

Use of selected lactic acid bacteria and quinoa flour for manufacturing novel yogurt-like beverages

A. Lorusso, R. Coda , M. Montemurro and C. G. Rizzello

Clinical and microbiological effect of a multispecies probiotic supplementation in celiac patients with Persistent IBS-type symptoms a randomized, double-blind, placebo-controlled, multicenter trial

R. Francavilla, M. Piccolo, A. Francavilla, L. Polimeno, F. Semeraro, F. Cristofori, S. Castellaneta, M. Barone, F. Indrio, M. Gobbetti, PhD,# and M. De Angelis

A Probiotic preparation hydrolyzes gliadin and protects intestinal cells from the Toxicity of Pro-Inflammatory Peptides

A. Giorgi, R. Cerrone, D. Capobianco, S. Filardo, P. Mancini, F. Zanni, S. Fanelli, P. Mastromarino and L. Mosca

The efficacy of the prenatal administration of Lactobacillus reuteri LR92 DSM 26866 on the prevention of infantile colic: a randomized control trial

M. A. Pourmirzaiee & F. Famouri & W. Moazeni & A. Hassanzadeh & M. Hajihashemi

An in vivo assessment of the cholesterollowering efficacy of Lactobacillus plantarum ECGC 13110402 in normal to mildly hypercholesterolaemic adults

A. Costabile, I. Buttarazzi, S. Kolida, S. Quercia, J. Baldini, J. R. Swann, P. Brigidi, G. R. Gibson

Effect of the Probiotic Lactobacillus rhamnosus LB21 on the Cariogenicity of Streptococcus mutans UA159 in a Dual-Species Biofilm Model

C. E Fernández , R. A Giacaman, L. M Tenuta, J. A Cury

Reversal of primary root caries lesions after daily intake of milk supplemented with fluoride and probiotic Lactobacilli in older adults

L. G. Petersson, K. Magnusson, U. Hakestam, A. Baigi, S. Twetman

Microbiological profiles in saliva and supragingival plaque from caries-active adolescents before and after a short-term daily Intake of milk supplemented with probiotic bacteria – a pilot study

M. O. Lexner, S. Blomqvist, G. Dahlén, S. Twetman

RGesreoarcwh atrthicl einhibition of oral mutans streptococci and candida by commercial probiotic lactobacilli – an in vitro study

P. Hasslöf, M. Hedberg, S. Twetman and C. Stecksén-Blicks

Coaggregation between probiotic bacteria and caries-associated strains: an in Vitro Study

L. Twetman, U. Larsen, N.-E. Fiehn, C. Stecksén-Blicks, S. Twetman

Effect of long-term consumption of milk supplemented with probiotic Lactobacilli and fluoride on dental caries and general health in preschool children: a cluster-randomized study

C Stecksén-Blicks, I Sjöström, S Twetman

Sugar fermentation in Probiotic bacteria, an in Vitro Study

M Hedberg, P Hasslöf, I Sjöström, S Twetman, C Stecksén-Blicks

Are the immunomodulatory properties of Lactobacillus rhamnosus CRL 1505 peptidoglycan common for all Lactobacilli during respiratory infection in malnourished mice?

Yanina Kolling, S. Salva, J. Villena, S. Alvarez

Nasal priming with immunobiotic Lactobacilli improves the adaptive immune response against influenza virus

F. R. Tonetti, Md Aminul Islam, M. G. Vizoso-Pinto, H. Takahashi, H. Kitazawa, J. Villena

Immunomodulatory properties of bacterium-like particles obtained from immunobiotic Lactobacilli: prospects for their use as mucosal adjuvants

F. R. Tonetti, L. Arce, S. Salva, S. Alvarez, H. Takahashi, H. Kitazawa, M. G. Vizoso-Pinto and J. Villena

Nasal priming with Lactobacillus rhamnosus CRL 1505 stimulates mononuclear phagocytes of immunocompromised malnourished mice: improvement of respiratory immune response

N Barbieri, S. Salva, M. Herrera, J. Villena, S. Alvarez

Efficient selection of new immunobiotic strains with antiviral effects in local and distal mucosal sites by using Porcine intestinal epitheliocytes

L. Albarracin, V. Garcia-Castillo, Y. Masumizu, Y. Indo, Md Aminul Islam, Y. Suda, A. Garcia-Cancino, H. Aso,
H. Takahashi, H. Kitazawa, and J. Villena

Oral vaccination with hepatitis e virus capsid protein and immunobiotic bacterium-like particles induce intestinal and systemic immunity in mice

LP Arce, MF Raya Tonetti, MP Raimondo, MF Müller, S Salva, S Álvarez, A Baiker, J Villena, M G Vizoso Pinto

Nasal immunization with recombinant chimeric pneumococcal protein and cell wall from immunobiotic bacteria improve resistance of infant mice to Streptococcus pneumoniae infection

J. Laiño, J. Villena, A. Suvorov, H. Zelaya, R. O. Moyano, S. Salva, S. Alvarez

Inorganic salts and intracellular polyphosphate inclusions play a role in the thermotolerance of the immunobiotic Lactobacillus rhamnosus CRL 1505

A. Correa Deza, M. Grillo-Puertas, S. Salva, V. A. Rapisarda, C. L. Gerez, G. Font de Valdez

Peptidoglycan from immunobiotic Lactobacillus rhamnosus improves resistance of infant mice to respiratory syncytial viral infectionand secondary Pneumococcal Pneumonia

P. Clua, P. Kanmani, H. Zelaya, A. Tada, A. K. M. Humayun Kober, S. Salva, S. Alvarez, H. Kitazawa, and J. Villena

Transcriptomic analysis of the innate antiviral immune response in Porcine intestinal epithelial cells: influence of immunobiotic lactobacilli

L. Albarracin, H. Kobayashi, H. Iida, N. Sato, T. Nochi, H. Aso, S. Salva, S. Alvarez, H. Kitazawa and J. Villena

The role of microbiota and immunobiotics in granulopoiesis of immunocompromised hosts

S. Salva and S. Alvarez

Lactobacillus rhamnosus CRL 1505 nasal administration improves recovery of T-cell mediated Immunity against pneumococcal Infection in malnourished mice

N Barbieri, M Herrera, S Salva, J Villena, S Alvarez

Immunobiotic Lactobacillus strains reduce small intestinal injury induced by intraepithelial Lymphocytes after toll-like receptor activation

A. Tada, H. Zelaya, P. Clua, S. Salva, S. Alvarez, H. Kitazawa, J. Villena

Nasal priming with immunobiotic Lactobacillus rhamnosus modulates inflammation-coagulation interactions and reduces influenza Virus-Associated Pulmonary Damage

H. Zelaya, A. Tada, M. G. Vizoso-Pinto, S. Salva, P. Kanmani, G.
Agüero, S. Alvarez, H. Kitazawa, J. Villena

Immunobiotic Lactobacilli reduce viral-associated pulmonary damage through the modulation of inflammation-coagulation interactions

H. Zelaya, K. Tsukida, E. Chiba, G. Marranzino, S. Alvarez, H. Kitazawa,
G. Agüero, J. Villena

Modulation of the inflammation coagulation interaction during pneumococcal pneumonia by immunobiotic Lactobacillus rhamnosus CRL 1505: Role of toll-like receptor

H. Zelaya, J. Villena, A. Gramajo Lopez, S. Alvarez, Gr. Agüero

Immunobiotic Lactobacillus rhamnosus strains differentially modulate antiviral immune response in porcine intestinal epithelial and antigen presenting cells

J. Villena, E. Chiba, M. G. Vizoso-Pinto, Y. Tomosada, T. Takahashi,
T. Ishizuka, H. Aso, S. Salva, S. Alvarez, H. Kitazawa

Non-viable Immunobiotic Lactobacillus rhamnosus CRL 1505 and Its peptidoglycan Improve systemic and respiratory innate immune response during recovery of immunocompromised-malnourished mice

Y. Kolling, S. Salva, J. Villena, G. Marranzino, S. Alvarez

Modulation of respiratory TLR3 anti-viral response by probiotic microorganisms: lessons learned from Lactobacillus rhamnosus CRL1505

H. Kitazawa, J. Villena

Dietary supplementation with Lactobacilli improves emergency granulopoiesis in protein-malnourished mice and enhances respiratory innate immune response

M. Herrera, S. Salva, J. Villena, N. Barbieri, G. Marranzino, S. Alvarez

Lactobacillus rhamnosus CRL 1505 beneficially modulates the immuno-coagulative response after pneumococcal infection in immunocompromised malnourished mice

H. Zelaya, J. Laiño, J. Villena, S. Alvarez, G.Agüero

Nasally administered Lactobacillus rhamnosus strains differentially modulate respiratory antiviral immune responses and induce protection against respiratory syncytial virus infection

Y. Tomosada, E. Chiba, H. Zelaya, T. Takahashi, K. Tsukida, H. Kitazawa,
S. Alvarez and J. Villena

Draft Genome Sequence of Lactobacillus rhamnosus CRL 1505, an Immunobiotic strain used in social food programs in Argentina

M. P. Taranto, J. Villena, S. Salva, S. Alvarez, G. Savoy de Giori, G. Font de Valdez, E. M. Hebert

Nasally Administered Lactobacillus rhamnosus accelerate the recovery of humoral immunity in B Lymphocyte-Deficient malnourished mice

N. Barbieri, J. Villena, M. Herrera, S. Salva, S. Alvarez

Immunobiotic Lactobacillus rhamnosus improves resistance of infant mice against respiratory syncytial virus infection

E. Chiba, Y. Tomosada, M. G. Vizoso-Pinto, S. Salva, T. Takahashi, K.
Tsukida, H. Kitazawa, S. Alvarez, J. Villena

Probiotics for everyone! The novel immunobiotic Lactobacillus rhamnosus CRL 1505 and the beginning of social probiotic programs in Argentina

J. Villena, S. Salva, M. Núñez, J. Corzo, R. Tolaba, J. Faedda, G. Font, S. Alvarez

Orally administered Lactobacillus rhamnosus modulates the respiratory immune response triggered by the viral pathogen-associatedmolecular pattern poly

J. Villena, E. Chiba, Y. Tomosada, S. Salva, G. Marranzino, H. Kitazawa, S. Alvarez

Dietary supplementation with Probiotics improves hematopoiesis in malnourished mice

S. Salva, M. C. Merino, G. Aguero, A. Gruppi, S. Alvarez

Whey protein coating bead improves the survival of the probiotic Lactobacillus rhamnosus CRL 1505 to low pH

C.L. Gerez, G. Font de Valdez, M.L. Gigante and C.R.F. Grosso

Stimulation of macrophages by immunobiotic Lactobacillus strains: influence beyond the intestinal tract

G. Marranzino, J. Villena, S. Salva, S. Alvarez

Development of a fermented goats Milk Containing Lactobacillus rhamnosus: in vivo study of health benefits

S. Salva, M.N. J. Villena, A. Ramón, G. Font, S. Alvarez

Immunomodulatory activity of Lactobacillus rhamnosus strains isolated from goat milk: impact on intestinal and respiratory infections

S. Salva, J. Villena, S. Alvarez

B. coagulans BC 4

K. marxianus fragilis B0399

L. plantarum LPLDL

L. reuteri LR 92

L. rhamnosus CRL 1505

L. rhamnosus LB21

L. rhamnosus SP 1

L. rhamnosus SP 1 + L. rhamnosus LB 21

PENTABIOCEL®

SYNBIO®